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KMID : 1142120150170010038
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Journal of Stroke
2015 Volume.17 No. 1 p.38 ~ p.53
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Case Characteristics, Hyperacute Treatment, and Outcome Information from the Clinical Research Center for Stroke-Fifth Division Registry in South Korea
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Kim Beom-Joon
Park Jong-Moo
Kang Kyu-Sik
Lee Soo-Joo
Ko Young-Chai
Kim Jae-Guk
Cha Jae-Kwan
Kim Dae-Hyun
Nah Hyun-Wook
Han Moon-Ku
Park Tai-Hwan
Park Sang-Soon
Lee Kyung-Bok
Lee Jun
Hong Keun-Sik
Cho Yong-Jin
Lee Byung-Chul
Yu Kyung-Ho
Oh Mi-Sun
Kim Dong-Eog
Ryu Wi-Sun
Cho Ki-Hyun
Kim Joon-Tae
Choi Jay-Chol
Kim Wook-Joo
Shin Dong-Ick
Yeo Min-Ju
Sohn Sung-Il
Hong Jeong-Ho
Lee June-Young
Lee Ji-Sung
Yoon Byung-Woo
Bae Hee-Joon
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Abstract
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Characteristics of stroke cases, acute stroke care, and outcomes after stroke differ according to geographical and cultural background. To provide epidemiological and clinical data on stroke care in South Korea, we analyzed a prospective multicenter clinical stroke registry, the Clinical Research Center for Stroke-Fifth Division (CRCS-5). Patients were 58% male with a mean age of 67.2±12.9 years and median National Institutes of Health Stroke Scale score of 3 [1-8] points. Over the 6 years of operation, temporal trends were documented including increasing utilization of recanalization treatment with shorter onset-to-arrival delay and decremental length of stay. Acute recanalization treatment was performed in 12.7% of cases with endovascular treatment utilized in 36%, but the proportion of endovascular recanalization varied across centers. Door-to-IV alteplase delay had a median of 45 [33-68] min. The rate of symptomatic hemorrhagic transformation (HT) was 7%, and that of any HT was 27% among recanalization-treated cases. Early neurological deterioration occurred in 15% of cases and were associated with longer length of stay and poorer 3-month outcomes. The proportion of mRS scores of 0-1 was 42% on discharge, 50% at 3 months, and 55% at 1 year after the index stroke. Recurrent stroke up to 1 year occurred in 4.5% of patients; the rate was higher among older individuals and those with neurologically severe deficits. The above findings will be compared with other Asian and US registry data in this article.
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KEYWORD
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Stroke registry, South Korea, Case profile, Hyperacute treatment, Thrombolysis, Outcome, Recurrent event
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